What symptom would most likely prompt a referral for a suspected malignancy in the neck?

A persistent and enlarging neck mass is a significant symptom that often raises concern for possible malignancy in the neck region. Such a mass that does not resolve or continues to increase in size over time can indicate the presence of neoplastic growth, whether benign or malignant. This is especially true in adults, where the likelihood of malignancy increases with duration and size.

Persistent neck masses warrant further evaluation due to the risk of underlying tumors, particularly in individuals with risk factors such as smoking, alcohol use, or a history of head and neck cancers. Medical professionals typically use the size, duration, and characteristics of the mass, along with patient history and risk factors, to guide their decision for referral to an otolaryngologist or oncologist for further investigation, including imaging studies and possible biopsy.

While the other symptoms listed, such as intermittent sore throat, change in voice quality, and swallowing difficulties can also be important in evaluating neck and throat issues, they are often not as immediately alarming as a persistent and enlarging mass. These symptoms may indicate other conditions such as infections, inflammatory processes, or functional issues that do not necessarily point to malignancy. Therefore, the distinct nature of a persistent, enlarging neck mass makes it the most likely symptom to prompt a